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BIODATA : |
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Name |
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Dr. MADHUMITA ROY, Ph.D |
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Designation |
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Head of the Department & Senior Scientific Officer,
Environmental Carcinogenesis & Toxicology |
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Postal address & Telephone No. |
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Chittaranjan National Cancer Institute
37 S. P. Mukherjee Road, Kolkata 700 026.
Telephone : 2476 –5101/02 extn 317,
Fax:91-33-2475-7606 |
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Residential address & Telephone No. |
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18/71, Dover Lane, Kolkata 700 029.
Mobile : 98310-18691. |
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Email |
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mitacnci@yahoo.co.in |
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Date of Birth |
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November 10, 1961 |
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Marital status |
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Married |
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Academic Attributes (beginning with last degree in reverse order) : |
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| Degree/ Certificate |
University/Board Year |
Division |
Specialisation/Area/Subjects |
| PhD |
Calcutta University -----> 1994 |
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BioPhysics |
| Post MSc |
Saha Institute of Nuclear Physics (Calcutta University) -----> 1986 |
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Bioscience |
| MSc |
Calcutta University -----> 1985 |
1st Class |
Physics (special paper Biophysics) |
| BSc Part II |
Calcutta University (Presidency College)----->1982 |
1st Class |
Physics (Hons)
[results published in 1983] |
| BSc Part I |
Calcutta University (Presidency College)----->1981 |
1st Div |
Physics (Hons), Maths,Chem, Eng. |
| Higher Secondary |
WBCHSE (South Point High School)----->1979 |
1st Div |
Eng, Beng,Phys, Chem, Maths, Biol |
| Madhyamik Pariksha |
WBBSE (St John’s Diocesan Girls’ High School)----->1977 |
1st Div |
Additional Maths |
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Awarded |
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Thesis entitled : Influence of various DNA damaging agents on V79 cells at different endpoints |
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Awarded National Scholarship scheme 1982-83 in the merit list of Bachelors Degree from University of Calcutta. |
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Awarded National Scholarship scheme for high position in Madhyamik Pariksha |
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Awarded “Professional Diploma in Clinical Research (PDCR)” and received a Certificate of Merit by Catalyst Clinical Services. |
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Awarded 1st prize at the Second World Congress on Cancer (WCC 2010) held at
Kottayam, Kerala, India from 3rd- 5th Sept, 2010. |
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Research & Training Experience : |
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| Duration |
Institution |
Particulars of work done |
| 1986-1994 |
Crystallography & Molecular Biology Division, Saha Institute of Nuclear Physics |
Ph.D. student (SINP Fellow).DNA damage and repair using
Chinese hamster V79 cells. |
| 1996-1997 |
Crystallography & Molecular Biology Division, Saha Institute of Nuclear Physics. |
Research Associate. Radiationresistance, chromosomal instability,
apoptosis in V79 cells. |
| 1997-1999 |
Dept of Cancer Chemoprevention, Chemoprev Chittaranjan Natl Cancer Inst, Kolkata. |
Research Associate in ICMR Project on Evaluation of the
chemopreventive efficiency of supplemental vitamins A and E in cervical intraepithelial neo-
plasia. Studied micronuclei and sister chromatid exchange in peripheral blood lymphocytes in CIN I and II patients before
and after vitamin treatment. |
| 1999-2001 |
Dept Env Carcin & Toxicol ,Chittaranjan Natl Cancer Inst, Kolkata. |
CSIR Research Associate Worked on induction of apoptosis in cultured mammalian cells by natural compounds. |
| 2001-till date |
Sr Scientific Officer, Chittaranjan Natl Cancer Inst, Kolkata. |
Tumor cell apoptosis: morphological and molecular characte ization, Cytogenetic anomalies caused by environmental toxic agents and chemical carcino gens, Chemoprevention by natural factors especially polyphenols from fruits,
tea and vegetables |
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Research specialization (Major Scientific Fields of Interest based on phytochemicals - prevention and chemosensitization : |
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Mammalian cell cultures (including cancer cells of human origin), radiation response of cells, mutagenesis, genetic toxicology, cytogenetic abnormalities (micronuclei, sister chromatid exchange, chromosome aberration etc), DNA damage (comet assay), gene amplification. |
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Mammalian cell apoptosis (in both normal and tumor cells) and its characterization by morphological (chromatin condensation), molecular (DNA fragmentation, caspase activity) and genetic (expression of pro- and anti-apoptotic genes) criteria |
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Cancer chemoprevention by natural polyphenolic compounds using cytogenetic anomalies. |
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Amelioration of arsenic induced toxicity by natural compounds, particularly tea and curcumin in both in vitro and in vivo systems. |
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Protection against oxidative stress created by arsenic by antioxidant activity of tea and curcumin in both in vitro and in vivo models. |
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Field trial intervention study using curcumin in human population residing in arsenic
affected areas in West Bengal. |
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Randomized field trial with black tea against inhibition of DNA repair in chronically arsenic affected skin lesions in West Bengal, India |
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Identification of some important tumor markers like protein kinase C, telomerase,
NFkB, TNF alpha, Histone deacetylase, Heat shock protein etc and their modulation by
plant derived natural compounds. |
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Sensitization and potentiation efficacy of tumor cells by natural compounds (by modulating such markers) towards apoptosis by conventional chemotherapeutic drugs. This is highly relevant in cancer therapy as presence of non-toxic phytochemicals reduce the effective drug dose and associated toxic side effects. |
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Other Academic Activities : |
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Executive Member, Organising Committee, National Workshop on HLPC and its Applications, September 20-22, 2003. |
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Workshop on Comet Assay: Application in Toxicology and Molecular Epidemiology, Industrial Toxicology Research Centre, Lucknow, Feb 7-11, 2003 |
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Speaker & Demonstrator, Workshop and Seminar on Fluorescence Microscopy, Nov 7,2003. (Organised by Electron Microscope Society of India). |
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Honoured as a lecturer in the AICTE sponsored QIP short term refresher’s course on the theme “Current Development and Direction for Drug Research and its Future Beyond 2025”, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, INDIA, 2005. |
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Invited speaker, Annual Conference organized by National Tea Research Foundation held at Peerless Inn, Kolkata on May 31, 2005, |
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Invited lecturer, Training programme on “Microscopy Techniques and its Application in Material Science and Biological Science” organised by Dept of Instrumentation Science, Jadavpur University, July, 2005. |
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Executive Committee Member, Environment Mutagen Society of India, 2006-2007 |
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Organizing Secretary, National Workshop on HPLC and Fluorescence Microscopy, Dec 6-8, 2007. |
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Participated in the Clinical Excellence Programme conducted by Aventis Pharma Limited, India at Kolkata, India. |
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Thesis Examiner, University of Kerala, |
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PhD viva voce examiner, Jadavpur University |
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Awarded “Professional Diploma in Clinical Research (PDCR)” and received a Certificate of Merit by Catalyst Clinical Services. |
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Reviewer of many National and International Scientific journals like Food and
Chemical Toxicology, Environmental Toxicology, Human Experimental Toxicology,
Journal of Ethnopharmacology, Mutation Research etc. |
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Teaching: |
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Examiner of PhD thesis of Jadavpur University, Kerala University. |
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Acted as a resource person of PhD course work of CNCI affiliated to University of Calcutta, Jadavpur University, West Bengal University of Health Sciences. |
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Dr Roy acted as a reviewer for the Extramural Project submitted to Indian Council of Medical Research, New Delhi. |
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Students from different Universities and Colleges are being trained by Dr Madhumita Roy for short term courses. |
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Other Professional Engagements : |
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Life Member, Environment Mutagen Society of India (EMSI) |
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Life Member, Indian Association for Cancer Research (IACR) |
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Member, Electron Microscope Society of India (Zonal Chapter Kolkata) |
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Life Member, Indian Science Congress Association |
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Extramural Grants : |
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National Tea Research Foundation, TEA BOARD |
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Dept of Science and Technology |
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Indian Council of Medical Research |
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Dept of Bio Technology |
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Council of Scientific and Industrial Resezarch |
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Hobbies : |
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Music |
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Travelling |
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Cooking |
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Curio collection |
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Art & craft |
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Latest Achievements : |
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Have been awarded 1st prize in the Second World Congress on Cancer (WCC-2010) held at Kottayam, Kerala, India from 3rd-5th September, 2010. |
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Awarded a certificate from National Professionals & Academicians Academy for YOUNG Talent Hunt 2012. |
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Paricipated in a TV programme at DD Bangla, “Sustho Bharat” programme on Arsenic
and Cancer. |
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Recipient of the “Rashtriya Gaurav Award” in 2013. |
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Recipient of “Best Citizens of India Award” in 2013. |
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Family Background : |
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